NRF1 Antikörper

Produktnummer ABIN8123448

Der Kaninchen Monoklonal anti-NRF1 Antikörper wird verwendet zum Nachweis von NRF1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA, IF und IP.

Kurzübersicht für NRF1 Antikörper (ABIN8123448)

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NRF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: AB2165

Produktdetails anti-NRF1 Antikörper

Verwendungszweck: Nrf1 Rabbit mAb

Spezifität: This antibody detects endogenous levels of Nrf1 protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu NRF1

Target: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Andere Bezeichnung: Nrf1

Hintergrund:

Synonyms: NRF1, Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal

Background: This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for ", nuclear factor (erythroid-derived 2)-like 1", which has an official symbol of NFE2L1. [provided by RefSeq, May 2014],

Gene Name: NRF1

Protein Name: Nrf1

Gen-ID: 4899

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha