NOTCH4 Antikörper (Cleaved-Val1467)

Produktnummer ABIN8123380

Der Kaninchen Polyklonal anti-NOTCH4 Antikörper (ABIN8123380) detektiert spezifisch NOTCH4 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Affe.

Kurzübersicht für NOTCH4 Antikörper (Cleaved-Val1467) (ABIN8123380)

Target: NOTCH4 (Notch 4 (NOTCH4))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOTCH4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NOTCH4 Antikörper

Bindungsspezifität: Cleaved-Val1467

Verwendungszweck: NOTCH4 (Cleaved-Val1467) Antibody

Spezifität: This antibody detects endogenous levels of Human,Monkey NOTCH4 (Cleaved-Val1467, protein was cleaved amino acid sequence between 1466-1467 )

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human NOTCH4 (Cleaved-Val1467)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NOTCH4

Target: NOTCH4 (Notch 4 (NOTCH4))

Andere Bezeichnung: NOTCH4

Hintergrund:

Synonyms: Neurogenic locus notch homolog protein 4 (Notch 4, hNotch4) [Cleaved into: Notch 4 extracellular truncation, Notch 4 intracellular domain]

Background: notch 4(NOTCH4) Homo sapiens This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which

Gene Name: NOTCH4 INT3

Protein Name: NOTCH4 (Cleaved-Val1467)

Gen-ID: 4855

UniProt: Q99466

Pathways: Notch Signalweg