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CPEB1 Antikörper (AA 451-550)

CPEB1 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN761501
  • Target Alle CPEB1 Antikörper anzeigen
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    Bindungsspezifität
    • 14
    • 10
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-550
    Reaktivität
    • 48
    • 4
    • 4
    Human
    Wirt
    • 45
    • 2
    • 1
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CPEB1 Antikörper ist unkonjugiert
    Applikation
    • 43
    • 24
    • 12
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Cow,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CPEB1
    Isotyp
    IgG
    Top Product
    Discover our top product CPEB1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    Andere Bezeichnung
    Cpeb1 (CPEB1 Produkte)
    Synonyme
    CEBP antikoerper, CPE-BP1 antikoerper, CPEB antikoerper, AU024112 antikoerper, Cpeb antikoerper, mCPEB antikoerper, CPEB1 antikoerper, cpeb1 antikoerper, ZOR-1 antikoerper, cepb1b antikoerper, fd15c06 antikoerper, wu:fd15c06 antikoerper, zorba antikoerper, cytoplasmic polyadenylation element binding protein 1 antikoerper, hypothetical protein antikoerper, cytoplasmic polyadenylation element binding protein 1 L homeolog antikoerper, cytoplasmic polyadenylation element binding protein 1b antikoerper, cytoplasmic polyadenylation element binding protein 1 S homeolog antikoerper, CPEB1 antikoerper, Cpeb1 antikoerper, cpeb1 antikoerper, LOAG_17395 antikoerper, cpeb1.L antikoerper, cpeb1b antikoerper, cpeb1.S antikoerper
    Hintergrund

    Synonyms: CPE-binding protein 1, CPE-BP1, CPEB 1, CPEB, CPEB1, CPEB1 protein, CPEB1_HUMAN, Cytoplasmic polyadenylation binding protein 1, Cytoplasmic polyadenylation element binding protein, Cytoplasmic polyadenylation element binding protein 1, Cytoplasmic polyadenylation element-binding protein 1, h-CEBP, hCPEB-1

    Background: Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation (By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity). Induces the assembly of stress granules in the absence of stress.

    Gen-ID
    64506
    Pathways
    Synaptic Membrane
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