MPRIP Antikörper

Produktnummer ABIN8123153

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MPRIP in WB, IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MPRIP Antikörper (ABIN8123153)

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPRIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-MPRIP Antikörper

Verwendungszweck: M-RIP Antibody

Spezifität: M-RIP Polyclonal Antibody detects endogenous levels of M-RIP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human M-RIP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MPRIP

Target: MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))

Andere Bezeichnung: M-RIP

Hintergrund:

Synonyms: MPRIP, KIAA0864, MRIP, RHOIP3, Myosin phosphatase Rho-interacting protein, M-RIP, Rho-interacting protein 3, RIP3, p116Rip

Background: function:Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.,similarity:Contains 1 PH domain.,similarity:Contains 2 PH domains.,subcellular location:Colocalizes with F-actin.,subunit:Binds F-actin through its N-terminus (By similarity). Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains.,

Gene Name: MPRIP

Protein Name: Myosin phosphatase Rho-interacting protein

Gen-ID: 23164

UniProt: Q6WCQ1