MYLK Antikörper (pTyr471)

Produktnummer ABIN8123150

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MYLK in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MYLK Antikörper (pTyr471) (ABIN8123150)

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYLK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MYLK Antikörper

Bindungsspezifität: pTyr471

Verwendungszweck: MLCK (Phospho Tyr471) Antibody

Spezifität: This antibody detects endogenous levels of Human,Mouse,Rat MLCK (Phospho Tyr471)

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human MLCK (Phospho Tyr471)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MYLK

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Andere Bezeichnung: MLCK

Hintergrund:

Synonyms: Myosin light chain kinase, smooth muscle (MLCK; smMLCK; EC 2.7.11.18; Kinase-related protein; KRP; Telokin) [Cleaved into: Myosin light chain kinase, smooth muscle, deglutamylated form]

Background: myosin light chain kinase(MYLK) Homo sapiens This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity.This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been

Gene Name: MYLK MLCK MLCK1 MYLK1

Protein Name: MLCK (Phospho Tyr471)

Gen-ID: 4638

UniProt: Q15746