Mast Cell Tryptase Antikörper (AA 200-275)

Produktnummer ABIN8122774

Der Maus Monoklonal anti-Mast Cell Tryptase Antikörper (Klon AB2346) (ABIN8122774) detektiert spezifisch Mast Cell Tryptase in IHC, WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Mast Cell Tryptase Antikörper (AA 200-275) (ABIN8122774)

Target: Mast Cell Tryptase

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Mast Cell Tryptase Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: AB2346

Produktdetails anti-Mast Cell Tryptase Antikörper

Bindungsspezifität: AA 200-275

Verwendungszweck: Mast cell tryptase mouse mAb

Spezifität: This antibody detects endogenous levels of Mast cell tryptase protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 200 - 275 of the human Mast cell tryptase protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Mast Cell Tryptase

Target: Mast Cell Tryptase

Hintergrund:

Synonyms: alpha II, Lung tryptase, Mast cell alpha II tryptase, Mast cell beta I tryptase, Mast cell protease 7, Mast cell protease II, MCP 7, Pituitary tryptase, Skin tryptase, TPS 1, TPS1, TPS2, TPSAB1, TPSAB1 protein, TPSB1, Tryptase 1, Tryptase alpha 1, tryptase alpha I included, Tryptase alpha II, tryptase alpha II included, tryptase alpha included, tryptase alpha/beta 1, Tryptase beta 1, tryptase beta I included, Tryptase I, tryptase I included, Tryptase III, Tryptase skin

Background: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13. 3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene

Gene Name: TPSAB1

Protein Name: Mast cell tryptase

Gen-ID: 7177

UniProt: Q15661