Lipin 1 Antikörper

Produktnummer ABIN8122666

Der Kaninchen Polyklonal anti-Lipin 1 Antikörper (ABIN8122666) detektiert spezifisch Lipin 1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Lipin 1 Antikörper (ABIN8122666)

Target: Lipin 1 (LPIN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lipin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Lipin 1 Antikörper

Verwendungszweck: lipin1 (phospho ser889) Antibody

Spezifität: This antibody detects endogenous levels of lipin1 ser889 at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human lipin1 ser889

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Lipin 1

Target: Lipin 1 (LPIN1)

Andere Bezeichnung: lipin1

Hintergrund:

Synonyms: Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1)

Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012],

Gene Name: LPIN1 KIAA0188

Protein Name: lipin1 ser889

Gen-ID: 23175

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process