Lrig1 Antikörper
Kurzübersicht für Lrig1 Antikörper (ABIN8122633)
Target
Alle Lrig1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- LRIG1 Antibody
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Spezifität
- LRIG1 Polyclonal Antibody detects endogenous levels of protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human protein
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- Lrig1 (Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
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Andere Bezeichnung
- LRIG1
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Hintergrund
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Background: domain:The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding. This interaction is abolished only when these two domains are deleted.,function:Act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.,induction:By EGF.,similarity:Contains 17 LRR (leucine-rich) repeats.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with EGFR/ERBB1, ERBB2, ERBB3 and ERBB4.,tissue specificity:Widely expressed.,
Gene Name: LRIG1 LIG1
Protein Name: Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1)
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Gen-ID
- 26018
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UniProt
- Q96JA1
Target
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