LRWD1 Antikörper (AA 395-445)
Kurzübersicht für LRWD1 Antikörper (AA 395-445) (ABIN8122629)
Target
Alle LRWD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 395-445
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Verwendungszweck
- LRWD1 Antibody
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Spezifität
- This antibody detects endogenous levels of LRWD1 at Human/Mouse
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human LRWD1 AA range: 395-445
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000,IHC 1:50-300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
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Andere Bezeichnung
- LRWD1
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Hintergrund
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Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
Gene Name: LRWD1 ORCA
Protein Name: LRWD1
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Gen-ID
- 222229
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UniProt
- Q9UFC0
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Pathways
- Chromatin Binding
Target
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