ITGA5 Antikörper (Cleaved-Arg894, Heavy Chain)

Produktnummer ABIN8122270

Der Kaninchen Polyklonal anti-ITGA5 Antikörper (ABIN8122270) detektiert spezifisch ITGA5 in WB, IHC und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für ITGA5 Antikörper (Cleaved-Arg894, Heavy Chain) (ABIN8122270)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-ITGA5 Antikörper

Bindungsspezifität: Cleaved-Arg894, Heavy Chain

Verwendungszweck: ITGA5 (heavy chain, Cleaved-Arg894) Antibody

Spezifität: This antibody detects endogenous levels of Human,Mouse ITGA5 (heavy chain, Cleaved-Arg894, protein was cleaved amino acid sequence between 894-895 )

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human ITGA5 (heavy chain, Cleaved-Arg894)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Andere Bezeichnung: ITGA5

Hintergrund:

Synonyms: Integrin alpha-5 (CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain, Integrin alpha-5 light chain]

Background: function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,

Gene Name: ITGA5 FNRA

Protein Name: ITGA5 (heavy chain, Cleaved-Arg894)

Gen-ID: 3678

UniProt: P08648

Pathways: Integrin Complex