ISR-beta Antikörper

Produktnummer ABIN8122223

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch ISR-beta in WB, IP, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für ISR-beta Antikörper (ABIN8122223)

Target: ISR-beta (Insulin Receptor beta (ISR-beta))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ISR-beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: AB2151

Produktdetails anti-ISR-beta Antikörper

Verwendungszweck: Insulin Receptor β Rabbit mAb

Spezifität: This antibody detects endogenous levels of Insulin Receptor β protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:2000-1:10000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu ISR-beta

Target: ISR-beta (Insulin Receptor beta (ISR-beta))

Andere Bezeichnung: Insulin Receptor beta

Hintergrund:

Synonyms: Insulin receptor, IR, CD antigen CD220, [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta]

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Gene Name: INSR

Protein Name: Insulin Receptor β

Gen-ID: 3643

UniProt: P06213