ISR-beta Antikörper (pTyr1345)

Produktnummer ABIN8122222

Der Kaninchen Polyklonal anti-ISR-beta Antikörper (ABIN8122222) detektiert spezifisch ISR-beta in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ISR-beta Antikörper (pTyr1345) (ABIN8122222)

Target: ISR-beta (Insulin Receptor beta (ISR-beta))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISR-beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ISR-beta Antikörper

Bindungsspezifität: pTyr1345

Verwendungszweck: Insulin Receptor β (Phospho Tyr1345) Antibody

Spezifität: This antibody detects endogenous levels of Human Insulin Receptor β (phospho-Tyr1345)

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Insulin Receptor beta (Tyr1345)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ISR-beta

Target: ISR-beta (Insulin Receptor beta (ISR-beta))

Andere Bezeichnung: Insulin Receptor beta

Hintergrund:

Synonyms: Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta]

Background: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Gene Name: INSR

Protein Name: Insulin Receptor β (Tyr1345)

Gen-ID: 3643

UniProt: P06213