HTRA2 Antikörper (pSer142)

Produktnummer ABIN8122111

Der Kaninchen Polyklonal anti-HTRA2 Antikörper (ABIN8122111) detektiert spezifisch HTRA2 in ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für HTRA2 Antikörper (pSer142) (ABIN8122111)

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-HTRA2 Antikörper

Bindungsspezifität: pSer142

Verwendungszweck: HtrA2 (phospho Ser142) Antibody

Spezifität: Phospho-HtrA2 (S142) Polyclonal Antibody detects endogenous levels of HtrA2 protein only when phosphorylated at S142.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human HtrA2 (phospho Ser142)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Andere Bezeichnung: HtrA2

Hintergrund:

Synonyms: HTRA2, OMI, PRSS25, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI

Background: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Gene Name: HTRA2

Protein Name: Serine protease HTRA2 mitochondrial

Gen-ID: 27429

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity