GTPBP4 Antikörper (AA 580-660)

Produktnummer ABIN8121834

Der Kaninchen Polyklonal anti-GTPBP4 Antikörper wird verwendet zum Nachweis von GTPBP4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für GTPBP4 Antikörper (AA 580-660) (ABIN8121834)

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTPBP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GTPBP4 Antikörper

Bindungsspezifität: AA 580-660

Verwendungszweck: NOG1 Antibody

Spezifität: NOG1 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 580-660

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GTPBP4

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Andere Bezeichnung: NOG1

Hintergrund:

Background: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008],

Gene Name: GTPBP4 CRFG NOG1

Protein Name: Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB)

Gen-ID: 23560

UniProt: Q9BZE4