Glutaredoxin 1 Antikörper (AA 8-58)

Produktnummer ABIN8121705

Der Kaninchen Polyklonal anti-Glutaredoxin 1 Antikörper wird verwendet zum Nachweis von Glutaredoxin 1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für Glutaredoxin 1 Antikörper (AA 8-58) (ABIN8121705)

Target: Glutaredoxin 1 (GRX1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glutaredoxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Glutaredoxin 1 Antikörper

Bindungsspezifität: AA 8-58

Verwendungszweck: Glutaredoxin-1 Antibody

Spezifität: This antibody detects endogenous levels of human Glutaredoxin-1

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Glutaredoxin-1 AA range: 8-58

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Andere Bezeichnung: Glutaredoxin-1

Hintergrund:

Synonyms: Glutaredoxin-1 (Thioltransferase-1; TTase-1)

Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],

Gene Name: GLRX GRX

Protein Name: Glutaredoxin-1

Gen-ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis