GLN1 Antikörper

Produktnummer ABIN8121699

Der Kaninchen Monoklonal anti-GLN1 Antikörper wird verwendet zum Nachweis von GLN1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC, IF, IP und ELISA.

Kurzübersicht für GLN1 Antikörper (ABIN8121699)

Target: GLN1 (Glutamine Synthetase (GLN1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser GLN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), ELISA

Klon: AB1655

Produktdetails anti-GLN1 Antikörper

Verwendungszweck: Glutamine Synthetase Rabbit mAb

Spezifität: This antibody detects endogenous levels of Glutamine Synthetase protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:1000-1:5000 | IHC, 1:1000-1:4000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu GLN1

Target: GLN1 (Glutamine Synthetase (GLN1))

Andere Bezeichnung: Glutamine Synthetase

Hintergrund:

Synonyms: GLUL, GLNS, Glutamine synthetase, GS, Glutamate decarboxylase, Glutamate-- ammonia ligase

Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

Gene Name: >>Arginine biosynthesis, >>Alanine, aspartate and glutamate metabolism, >>Glyoxylate and dicarboxylate metabolism, >>Nitrogen metabolism, >>Metabolic pathways, >>Biosynthesis of amino acids, >>Necroptosis, >>Glutamatergic synapse, >>GABAergic synapse

Protein Name: Glutamine Synthetase

Gen-ID: 2752

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion