GLUL Antikörper (AA 400-500)

Produktnummer ABIN8121691

Der Maus Monoklonal anti-GLUL Antikörper (Klon AB2426) (ABIN8121691) detektiert spezifisch GLUL in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GLUL Antikörper (AA 400-500) (ABIN8121691)

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GLUL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: AB2426

Produktdetails anti-GLUL Antikörper

Bindungsspezifität: AA 400-500

Verwendungszweck: Gl Syn/Glutamine Synthetase mouse mAb

Spezifität: This antibody detects endogenous levels of Gl Syn/Glutamine Synthetase protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 400 - 500 of the human Beta Tubulin protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu GLUL

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Andere Bezeichnung: Gl Syn/Glutamine Synthetase

Hintergrund:

Synonyms: GLUL,GLNS,Glutamine synthetase,GS,Glutamate decarboxylase,Glutamate-- ammonia ligase

Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

Gene Name: GLUL

Protein Name: Gl Syn/Glutamine Synthetase

Gen-ID: 2752

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion