GRIK2 Antikörper (AA 119-169)

Produktnummer ABIN8121686

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GRIK2 in IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GRIK2 Antikörper (AA 119-169) (ABIN8121686)

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GRIK2 Antikörper

Bindungsspezifität: AA 119-169

Verwendungszweck: GRIK2 (GluR6) Antibody

Spezifität: GRIK2(GluR6) protein(A240) detects endogenous levels of GRIK2(GluR6)

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Peptide of GRIK2 (GluR6) AA range: 119-169

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-200. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GRIK2

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Andere Bezeichnung: GRIK2

Hintergrund:

Synonyms: Glutamate receptor, ionotropic kainate 2 (Excitatory amino acid receptor 4, EAA4, Glutamate receptor 6, GluR-6, GluR6)

Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],

Gene Name: GRIK2

Protein Name: Glutamate receptor, ionotropic kainate 2 (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)

Gen-ID: 2898

UniProt: Q13002

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity