FH Antikörper

Produktnummer ABIN8121541

Der Kaninchen Polyklonal anti-FH Antikörper (ABIN8121541) detektiert spezifisch FH in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für FH Antikörper (ABIN8121541)

Target: FH (Fumarate Hydratase (FH))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FH Antikörper

Verwendungszweck: FH Antibody

Spezifität: The antibody detects endogenous fumarase proteins.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein of Fumarate hydratase, mitochondrial

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu FH

Target: FH (Fumarate Hydratase (FH))

Andere Bezeichnung: FH

Hintergrund:

Synonyms: Fumarate hydratase, mitochondrial (Fumarase) (EC 4.2.1.2)

Background: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008],

Gene Name: FH

Protein Name: Fumarate hydratase, mitochondrial

Gen-ID: 2271

UniProt: P07954