FBXO22 Antikörper (AA 182-232)

Produktnummer ABIN8121356

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FBXO22 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für FBXO22 Antikörper (AA 182-232) (ABIN8121356)

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXO22 Antikörper

Bindungsspezifität: AA 182-232

Verwendungszweck: FBX22 Antibody

Spezifität: This antibody detects endogenous levels of FBX22 at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FBX22 AA range: 182-232

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu FBXO22

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Andere Bezeichnung: FBX22

Hintergrund:

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],

Gene Name: FBXO22 FBX22

Protein Name: FBX22

Gen-ID: 26263

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development