FBXW2 Antikörper (AA 155-205)

Produktnummer ABIN8121352

Der Kaninchen Polyklonal anti-FBXW2 Antikörper (ABIN8121352) detektiert spezifisch FBXW2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für FBXW2 Antikörper (AA 155-205) (ABIN8121352)

Target: FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXW2 Antikörper

Bindungsspezifität: AA 155-205

Verwendungszweck: FBXW2 Antibody

Spezifität: This antibody detects endogenous levels of FBXW2 at Human/Mouse/Rat

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FBXW2 AA range: 155-205

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu FBXW2

Target: FBXW2 (F-Box and WD Repeat Domain Containing 2 (FBXW2))

Andere Bezeichnung: FBXW2

Hintergrund:

Background: F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains.This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008],

Gene Name: FBXW2 FBW2 FWD2

Protein Name: FBXW2

Gen-ID: 26190

UniProt: Q9UKT8