Dystroglycan Antikörper (AA 830-910)
Kurzübersicht für Dystroglycan Antikörper (AA 830-910) (ABIN8121095)
Target
Alle Dystroglycan (DAG1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 830-910
-
Verwendungszweck
- DAG1 Antibody
-
Spezifität
- DAG1 Polyclonal Antibody detects endogenous levels of protein.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- Synthesized peptide derived from human protein . at AA range: 830-910
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C/1 year
-
Haltbarkeit
- 12 months
-
-
- Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))
-
Andere Bezeichnung
- DAG1
-
Hintergrund
-
Background: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Nov 2015],
Gene Name: DAG1
Protein Name: Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG)Beta-dystroglycan (Beta-DG)]
-
Gen-ID
- 1605
-
UniProt
- Q14118
-
Pathways
- Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
Target
-