Dynamin 1-Like Antikörper (pSer616)

Produktnummer ABIN8121081

Der Kaninchen Monoklonal anti-Dynamin 1-Like Antikörper wird verwendet zum Nachweis von Dynamin 1-Like in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IF und IP.

Kurzübersicht für Dynamin 1-Like Antikörper (pSer616) (ABIN8121081)

Target: Dynamin 1-Like (DNM1L)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: AB2205

Produktdetails anti-Dynamin 1-Like Antikörper

Bindungsspezifität: pSer616

Verwendungszweck: DRP1 (Phospho Ser616) Rabbit mAb

Spezifität: The antibody detects endogenous levels of DRP1 protein only when phosphorylated at Ser616. The antibody does not cross-react with DRP1 phosphorylated at other sites.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DRP1

Hintergrund:

Synonyms: DNM1L, DLP1, DRP1, Dynamin-1-like protein, Dnm1p/Vps1p-like protein, DVLP, Dynamin family member proline-rich carboxyl-terminal domain less, Dymple, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, HdynIV, Dynamin-rela

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer&apos, s disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) . Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013],

Gene Name: DNM1L

Protein Name: DRP1 (Phospho Ser616)

Gen-ID: 10059

UniProt: O00429