Dynamin 1-Like Antikörper (pSer616)

Produktnummer ABIN8121080

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Dynamin 1-Like in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für Dynamin 1-Like Antikörper (pSer616) (ABIN8121080)

Target: Dynamin 1-Like (DNM1L)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Dynamin 1-Like Antikörper

Bindungsspezifität: pSer616

Verwendungszweck: DRP1 (Phospho Ser616) Antibody

Spezifität: Phospho-DRP1 (S616) Polyclonal Antibody detects endogenous levels of DRP1 protein only when phosphorylated at S616(human), S622(mouse), S635(rat)

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human DRP1 (Ser616)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DRP1

Hintergrund:

Synonyms: Dynamin-1-like protein (EC 3.6.5.5) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-like protein) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV) (Dynamin-related protein 1)

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013],

Gene Name: DNM1L DLP1 DRP1

Protein Name: DRP1 (Ser616)

Gen-ID: 10059

UniProt: O00429