COX2 Antikörper

Produktnummer ABIN8120863

Der Kaninchen Monoklonal anti-COX2 Antikörper (Klon AB1663) (ABIN8120863) detektiert spezifisch COX2 in WB, IHC, ELISA, IP und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für COX2 Antikörper (ABIN8120863)

Target: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser COX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: AB1663

Produktdetails anti-COX2 Antikörper

Verwendungszweck: MTCO2 Rabbit mAb

Spezifität: This antibody detects endogenous levels of MTCO2 protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu COX2

Target: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Andere Bezeichnung: MTCO2

Hintergrund:

Synonyms: Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)

Background: cofactor:Copper A. , disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110], also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood. , disease:Defects in MT-CO2 are associated with tumor formation. , function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. , similarity:Belongs to the cytochrome c oxidase subunit 2 family. ,

Gene Name: MT-CO2 COII COXII MTCO2

Protein Name: MTCO2

Gen-ID: 4513

UniProt: P00403

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation