COX2 Antikörper (AA 40-120)

Produktnummer ABIN8120862

Der Kaninchen Polyklonal anti-COX2 Antikörper wird verwendet zum Nachweis von COX2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für COX2 Antikörper (AA 40-120) (ABIN8120862)

Target: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-COX2 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: MTCO2 Antibody

Spezifität: COX2 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu COX2

Target: COX2 (Cytochrome C Oxidase Subunit II (COX2))

Andere Bezeichnung: MTCO2

Hintergrund:

Background: cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110], also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family.,

Gene Name: MT-CO2 COII COXII MTCO2

Protein Name: Cytochrome c oxidase subunit 2 (Cytochrome c oxidase polypeptide II)

Gen-ID: 4513

UniProt: P00403

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation