DMP1 Antikörper (AA 430-510)

Produktnummer ABIN8120790

Der Kaninchen Polyklonal anti-DMP1 Antikörper wird verwendet zum Nachweis von DMP1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für DMP1 Antikörper (AA 430-510) (ABIN8120790)

Target: DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DMP1 Antikörper

Bindungsspezifität: AA 430-510

Verwendungszweck: DMP1 Antibody

Spezifität: DMP1 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 430-510

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DMP1

Target: DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))

Andere Bezeichnung: DMP1

Hintergrund:

Background: Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conser

Gene Name: DMP1

Protein Name: Dentin matrix acidic phosphoprotein 1 (DMP-1) (Dentin matrix protein 1)

Gen-ID: 1758

UniProt: Q13316