CFHR5 Antikörper (AA 353-403)

Produktnummer ABIN8120724

Der Kaninchen Polyklonal anti-CFHR5 Antikörper wird verwendet zum Nachweis von CFHR5 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für CFHR5 Antikörper (AA 353-403) (ABIN8120724)

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CFHR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CFHR5 Antikörper

Bindungsspezifität: AA 353-403

Verwendungszweck: FHR5 Antibody

Spezifität: This antibody detects endogenous levels of FHR5 at Human

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FHR5 AA range: 353-403

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CFHR5

Target: CFHR5 (Complement Factor H-Related 5 (CFHR5))

Andere Bezeichnung: FHR5

Hintergrund:

Synonyms: Complement factor H-related protein 5 (FHR-5)

Background: This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation.The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010],

Gene Name: CFHR5 CFHL5 FHR5

Protein Name: FHR5

Gen-ID: 81494

UniProt: Q9BXR6