Coagulation Factor X Antikörper (Cleaved-Arg179, Light Chain)

Produktnummer ABIN8120642

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Coagulation Factor X in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Coagulation Factor X Antikörper (Cleaved-Arg179, Light Chain) (ABIN8120642)

Target: Coagulation Factor X (F10)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Coagulation Factor X Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Coagulation Factor X Antikörper

Bindungsspezifität: Cleaved-Arg179, Light Chain

Verwendungszweck: FA10 (light chain, Cleaved-Arg179) Antibody

Spezifität: This antibody detects endogenous levels of Human FA10 (light chain, Cleaved-Arg179, protein was cleaved amino acid sequence between )

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human FA10 (light chain, Cleaved-Arg179)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Coagulation Factor X

Target: Coagulation Factor X (F10)

Andere Bezeichnung: FA10

Hintergrund:

Synonyms: Coagulation factor X (EC 3.4.21.6, Stuart factor, Stuart-Prower factor) [Cleaved into: Factor X light chain, Factor X heavy chain, Activated factor Xa heavy chain]

Background: catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.,function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.,online information:Factor X entry,PTM:N- and O-glycosylated.,PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,PTM:The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.,tissue specificity:Plasma, synthesized in the liver.,

Gene Name: F10

Protein Name: FA10 (light chain, Cleaved-Arg179)

Gen-ID: 2159

UniProt: P00742