Claudin 7 Antikörper (AA 100-211)

Produktnummer ABIN8120616

Der Maus Monoklonal anti-Claudin 7 Antikörper wird verwendet zum Nachweis von Claudin 7 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für Claudin 7 Antikörper (AA 100-211) (ABIN8120616)

Target: Claudin 7 (CLDN7)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Claudin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: AB1433

Produktdetails anti-Claudin 7 Antikörper

Bindungsspezifität: AA 100-211

Verwendungszweck: Claudin 7 mouse mAb

Spezifität: The antibody can specifically recognize human Claudin 7 protein. In western blotting of LnCap cell lysate, the antibody can label a 22 kDa band corresponding to Claudin 7.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 211 of the human Claudin 7 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Claudin 7

Target: Claudin 7 (CLDN7)

Andere Bezeichnung: Claudin 7

Hintergrund:

Synonyms: CEPTR L2, CEPTRL 2, CEPTRL2, Claudin 1, Claudin 7, Claudin 9, Claudin-7, Claudin1, Claudin7, Claudin9, CLD7_HUMAN, CLDN 7, CLDN-7, CLDN7, Clostridium perfringens enterotoxin receptor like 2, CPETR L2, CPETRL 2, CPETRL2, Hs. 84359

Background: Claudin 7 is a 22 kDa membrane protein, belonging to the tight junction protein family. Claudin family proteins play an important role in cell polarity, signal transduction and the pathogenesis of a variety of malignant tumors. It has been reported that compared with non neoplastic mucosal tissues, the expression of claudin 7 in laryngeal squamous cell carcinoma is down-regulated, and the expression level is related to distant metastasis, which can be used as a potential predictor of poor prognosis. Therefore, claudin 7 may be a useful immunohistochemical marker for the diagnosis, metastasis and prognosis of laryngeal cancer.

Gene Name: CLDN7 CEPTRL2 CPETRL2

Protein Name: Claudin 7

Gen-ID: 1366

UniProt: O95471

Pathways: Hepatitis C