Claudin 3 Antikörper (AA 150-220)

Produktnummer ABIN8120604

Der Maus Monoklonal anti-Claudin 3 Antikörper wird verwendet zum Nachweis von Claudin 3 in Proben von Human. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für Claudin 3 Antikörper (AA 150-220) (ABIN8120604)

Target: Claudin 3 (CLDN3)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Claudin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon: AB1534

Produktdetails anti-Claudin 3 Antikörper

Bindungsspezifität: AA 150-220

Verwendungszweck: Claudin 3 mouse mAb

Spezifität: This antibody detects endogenous levels of Claudin 3 protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 220 of the human Claudin 3 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Claudin 3

Target: Claudin 3 (CLDN3)

Andere Bezeichnung: Claudin 3

Hintergrund:

Synonyms: Clostridium perfringens enterotoxin receptor 2, Rat ventral prostate. 1 protein homolog

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Gene Name: CLDN3

Protein Name: Claudin 3

Gen-ID: 1365

UniProt: O15551

Pathways: Hepatitis C