Claudin 18 Antikörper (AA 150-261)
Kurzübersicht für Claudin 18 Antikörper (AA 150-261) (ABIN8120594)
Target
Alle Claudin 18 (CLDN18) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 150-261
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Verwendungszweck
- Claudin 18 Rabbit mAb (Ready to Use)
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Spezifität
- The antibody can specifically recognize both human Claudin 18. 1 and Claudin 18. 2 protein.
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Aufreinigung
- The antibody was purified by protein A affinity chromatography.
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Immunogen
- A synthetic peptide corresponding to the amino acid region 150 - 261 of the human Claudin 18 protein.
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Isotyp
- IgG
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Applikationshinweise
- It has been optimized for direct use, requiring no further dilution.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 4°C. Avoid freeze.
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- Claudin 18 (CLDN18)
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Andere Bezeichnung
- Claudin 18
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Hintergrund
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Synonyms: Claudin 18,Claudin-18,CLD18_HUMAN,CLDN18,SFTA5,SFTPJ
Background: Claudin 18 is a 27 kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.
Gene Name: CLDN18
Protein Name: Claudin 18
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Gen-ID
- 51208
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UniProt
- P56856
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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