CHD9 Antikörper

Produktnummer ABIN8120548

Der Kaninchen Polyklonal anti-CHD9 Antikörper (ABIN8120548) detektiert spezifisch CHD9 in IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für CHD9 Antikörper (ABIN8120548)

Target: CHD9 (Chromodomain Helicase DNA Binding Protein 9 (CHD9))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHD9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CHD9 Antikörper

Verwendungszweck: CHD9 Antibody

Spezifität: CHD9 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-300. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CHD9

Target: CHD9 (Chromodomain Helicase DNA Binding Protein 9 (CHD9))

Andere Bezeichnung: CHD9

Hintergrund:

Background: function:Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis.,PTM:Phosphorylated on serine and tyrosine residues.,sequence caution:Wrong choice of frame.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,subunit:Interacts with PPARA. Probably interacts with ESR1 and NR1I3.,tissue specificity:Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.,

Gene Name: CHD9 KIAA0308 KISH2 PRIC320 AD-013 x0008

Protein Name: Chromodomain-helicase-DNA-binding protein 9 (CHD-9) (EC 3.6.4.12) (ATP-dependent helicase CHD9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin-remodeling factor CHROM1) (Kismet homolog 2) (PPAR-alpha-interacting complex protein 320 kDa) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein)

Gen-ID: 80205

UniProt: Q3L8U1

Pathways: Regulation of Lipid Metabolism by PPARalpha