CBX1 Antikörper (pThr51)

Produktnummer ABIN8120538

Der Kaninchen Polyklonal anti-CBX1 Antikörper wird verwendet zum Nachweis von CBX1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für CBX1 Antikörper (pThr51) (ABIN8120538)

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CBX1 Antikörper

Bindungsspezifität: pThr51

Verwendungszweck: HP1-β (Phospho Thr51) Antibody

Spezifität: This antibody detects endogenous levels of HP1-β (Phospho-Thr51) at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human HP1-beta (Phospho-Thr51)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CBX1

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Andere Bezeichnung: HP1-beta

Hintergrund:

Synonyms: Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)

Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],

Gene Name: CBX1 CBX

Protein Name: HP1-β (Phospho-Thr51)

Gen-ID: 10951

UniProt: P83916