CENPM Antikörper (AA 30-110)

Produktnummer ABIN8120458

Der Kaninchen Polyklonal anti-CENPM Antikörper (ABIN8120458) detektiert spezifisch CENPM in WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für CENPM Antikörper (AA 30-110) (ABIN8120458)

Target: CENPM (Centromere Protein M (CENPM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CENPM Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: CENP-M Antibody

Spezifität: This antibody detects endogenous levels of human CENP-M

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CENP-M AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CENPM

Target: CENPM (Centromere Protein M (CENPM))

Andere Bezeichnung: CENP-M

Hintergrund:

Synonyms: Centromere protein M (CENP-M, Interphase centromere complex protein 39, Proliferation-associated nuclear element protein 1)

Background: The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Gene Name: CENPM C22orf18 ICEN39 PANE1

Protein Name: CENP-M

Gen-ID: 79019

UniProt: Q9NSP4