CTSA Antikörper (Cleaved-Met327)

Produktnummer ABIN8120272

Der Kaninchen Polyklonal anti-CTSA Antikörper (ABIN8120272) detektiert spezifisch CTSA in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für CTSA Antikörper (Cleaved-Met327) (ABIN8120272)

Target: CTSA (Cathepsin A (CTSA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTSA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CTSA Antikörper

Bindungsspezifität: Cleaved-Met327

Verwendungszweck: PPGB (20k, Cleaved-Met327) Antibody

Spezifität: This antibody detects endogenous levels of Human,Mouse PPGB (20k, Cleaved-Met327, protein was cleaved amino acid sequence between 326-327 )

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human PPGB (20k, Cleaved-Met327)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CTSA

Target: CTSA (Cathepsin A (CTSA))

Andere Bezeichnung: PPGB

Hintergrund:

Synonyms: Lysosomal protective protein (EC 3.4.16.5, Carboxypeptidase C, Carboxypeptidase L, Cathepsin A, Protective protein cathepsin A, PPCA, Protective protein for beta-galactosidase) [Cleaved into: Lysosomal protective protein 32 kDa chain, Lysosomal protective protein 20 kDa chain]

Background: catalytic activity:Release of a C-terminal amino acid with broad specificity.,disease:Defects in CTSA are the cause of galactosialidosis [MIM:256540]. It is an autosomal recessive disease.,function:Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins.,similarity:Belongs to the peptidase S10 family.,subunit:Heterodimer of a 32 kDa chain and a 20 kDa chain, disulfide-linked.,

Gene Name: CTSA PPGB

Protein Name: PPGB (20k, Cleaved-Met327)

Gen-ID: 5476

UniProt: P10619