CA9 Antikörper

Produktnummer ABIN8120183

Dieser Maus Monoklonal Antikörper detektiert spezifisch CA9 in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CA9 Antikörper (ABIN8120183)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CA9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: AB2460

Produktdetails anti-CA9 Antikörper

Verwendungszweck: CA IX mouse mAb

Spezifität: The antibody can specifically recognize human CA IX protein.

Aufreinigung: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: Recombinant protein of the human CA IX protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Andere Bezeichnung: CA IX

Hintergrund:

Synonyms: G250, MN, Carbonic anhydrase 9, Carbonate dehydratase IX, Carbonic anhydrase IX, CA-IX, CAIX, Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250, RCC-associated antigen G250, pMW1

Background: CA IX (Carbonic Anhydrase IX) is a transmembrane protein belonging to the carbonic anhydrase family. It catalyzes the conversion of carbon dioxide and water into bicarbonate and protons in the extracellular environment. CA IX is minimally expressed in normal tissues, primarily found in gastrointestinal epithelial cells, but is highly expressed in various malignant tumors, such as clear cell renal carcinoma, breast cancer, and pancreatic cancer. Its expression is significantly upregulated under hypoxic conditions. Therefore, CA IX has been widely studied as a tumor biomarker and a potential therapeutic target.

Gene Name: CA9

Protein Name: CA IX

Gen-ID: 768

UniProt: Q16790