Bystin Antikörper (AA 127-177)

Produktnummer ABIN8120058

Der Kaninchen Polyklonal anti-Bystin Antikörper wird verwendet zum Nachweis von Bystin in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für Bystin Antikörper (AA 127-177) (ABIN8120058)

Target: Bystin (BYST)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Bystin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Bystin Antikörper

Bindungsspezifität: AA 127-177

Verwendungszweck: BYST Antibody

Spezifität: This antibody detects endogenous levels of BYST at Human/Mouse/Rat

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human BYST AA range: 127-177

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Bystin

Target: Bystin (BYST)

Andere Bezeichnung: BYST

Hintergrund:

Background: Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi. [provided by RefSeq, Jul 2008],

Gene Name: BYSL

Protein Name: BYST

Gen-ID: 705

UniProt: Q13895