APLP1 Antikörper (AA 360-440)

Produktnummer ABIN8119714

Der Kaninchen Polyklonal anti-APLP1 Antikörper (ABIN8119714) detektiert spezifisch APLP1 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für APLP1 Antikörper (AA 360-440) (ABIN8119714)

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APLP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-APLP1 Antikörper

Bindungsspezifität: AA 360-440

Verwendungszweck: APLP-1 Antibody

Spezifität: APLP-1 Polyclonal Antibody detects endogenous levels of APLP-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from APLP-1 . at AA range: 360-440

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu APLP1

Target: APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))

Andere Bezeichnung: APLP-1

Hintergrund:

Synonyms: APLP1, Amyloid-like protein 1, APLP, APLP-1

Background: This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Gene Name: APLP1

Protein Name: Amyloid-like protein 1

Gen-ID: 333

UniProt: P51693

Pathways: cAMP Metabolic Process