alpha-SMA Antikörper

Produktnummer ABIN8119694

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch alpha-SMA in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für alpha-SMA Antikörper (ABIN8119694)

Target: alpha-SMA

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails

Verwendungszweck: α-SMA Antibody

Spezifität: α-SMA Polyclonal Antibody detects endogenous levels of α-SMA protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human alpha-SMA.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Antigendetails

Target: alpha-SMA

Hintergrund:

Synonyms: ACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1, ACTA2, ACTSA, ACTVS, GIG46, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTC1, ACTC, Actin, alpha cardiac muscle 1, Alpha-cardiac actinACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1, ACTA2, ACTSA, ACTVS, GIG46, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTC1, ACTC, Actin, alpha cardiac muscle 1, Alpha-cardiac actin

Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008],

Gene Name: ACTA1/ACTA2/ACTC1

Protein Name: Actin alpha skeletal muscle/Actin aortic smooth muscle/Actin alpha cardiac muscle 1

Gen-ID: 59

UniProt: P68133