PACAP Antikörper (AA 1-50)

Produktnummer ABIN8119600

Der Kaninchen Polyklonal anti-PACAP Antikörper (ABIN8119600) detektiert spezifisch PACAP in IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PACAP Antikörper (AA 1-50) (ABIN8119600)

Target: PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACAP Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PACAP Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: PACAP Antibody

Spezifität: The antibody detects endogenous PACAP

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PACAP

Target: PACAP (ADCYAP1) (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1))

Andere Bezeichnung: PACAP

Hintergrund:

Synonyms: Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein, pERp1, Proapoptotic caspase adapter protein)

Background: function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,

Gene Name: PACAP HSPC190

Protein Name: Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein) (pERp1) (Proapoptotic caspase adapter protein)

Gen-ID: 51237

UniProt: Q8WU39

Pathways: Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Hormone Activity, cAMP Metabolic Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Regulation of G-Protein Coupled Receptor Protein Signaling