ASCC1 Antikörper (AA 289-339)

Produktnummer ABIN8119529

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ASCC1 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für ASCC1 Antikörper (AA 289-339) (ABIN8119529)

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ASCC1 Antikörper

Bindungsspezifität: AA 289-339

Verwendungszweck: ASCC1 Antibody

Spezifität: This antibody detects endogenous levels of ASCC1 at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human ASCC1 AA range: 289-339

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu ASCC1

Target: ASCC1 (Activating Signal Cointegrator 1 Complex Subunit 1 (ASCC1))

Andere Bezeichnung: ASCC1

Hintergrund:

Background: This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Gene Name: ASCC1 CGI-18

Protein Name: ASCC1

Gen-ID: 51008

UniProt: Q8N9N2