BEX1 Antikörper (AA 55-125)

Produktnummer ABIN760871

Der Kaninchen Polyklonal Anti-BEX1-Antikörper wurde für ELISA, WB, IHC (p), IF (cc), IF (p) und IHC (fro) validiert. Er ist geeignet, BEX1 in Proben von Human zu detektieren.

Kurzübersicht für BEX1 Antikörper (AA 55-125) (ABIN760871)

Target: BEX1 (Brain Expressed, X-Linked 1 (BEX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BEX1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-BEX1 Antikörper

Bindungsspezifität: AA 55-125

Homologie: Human,Mouse,Rat,Cow,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HBEX2/Bex1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BEX1

Target: BEX1 (Brain Expressed, X-Linked 1 (BEX1))

Andere Bezeichnung: Bex1

Hintergrund:

Synonyms: BEX2, Brain expressed X linked 1, HBEX2, Protein BEX1, BEX1_HUMAN.

Background: The brain-expressed X-linked (Bex) family of proteins is expressed in the central nervous system, with highest levels detected in cerebellum, temporal lobe and pituitary tissues. Bex1 plays an important role in neuronal differentiation in response to nerve growth factor (NGF), as well as in cell cycle progression. Bex1 is a highly ubiquitinated protein and acts as a link between the cell cycle and neurotrophic factor signaling. Bex2 interacts with LMO2, thereby regulating the transcriptional activity of a DNA-binding complex. Bex1 and Bex 2 are widely expressed outside of the central nervous system with high expression in the liver. Bex1 and Bex2 shuttle between the cytoplasm and the nucleus. Though the role of Bex1 is largely unknown, it may function by coordinating internal cellular states with the ability of cells to respond to external signals.

Gen-ID: 55859

Pathways: Neurotrophin Signalübertragung