SMYD3 Antikörper (AA 101-200)
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- Target Alle SMYD3 Antikörper anzeigen
- SMYD3 (SET and MYND Domain Containing 3 (SMYD3))
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Bindungsspezifität
- AA 101-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMYD3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human
- Homologie
- Mouse,Rat,Cow,Sheep,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SMYD3
- Isotyp
- IgG
- Top Product
- Discover our top product SMYD3 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SMYD3 (SET and MYND Domain Containing 3 (SMYD3))
- Andere Bezeichnung
- Smyd3 (SMYD3 Produkte)
- Synonyme
- KMT3E antikoerper, ZMYND1 antikoerper, ZNFN3A1 antikoerper, bA74P14.1 antikoerper, 2410008A19Rik antikoerper, Zmynd1 antikoerper, SET and MYND domain containing 3 antikoerper, SMYD3 antikoerper, Smyd3 antikoerper
- Hintergrund
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Synonyms: SET and MYND domain containing 3, SET and MYND domain containing protein 3, SMYD 3, SMYD3 protein, Zinc finger MYND domain containing 1, Zinc finger MYND domain containing protein 1, Zinc finger protein subfamily 3A MYND domain containing 1, ZMYND 1, ZMYND1, ZNFN3A1, SMYD3_HUMAN.
Background: SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.
- Gen-ID
- 64754
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