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SMYD3 Antikörper (AA 101-200)

Der Kaninchen Polyklonal Anti-SMYD3-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, SMYD3 in Proben von Human zu detektieren.
Produktnummer ABIN760586

Kurzübersicht für SMYD3 Antikörper (AA 101-200) (ABIN760586)

Target

Alle SMYD3 Antikörper anzeigen
SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

Reaktivität

  • 54
  • 18
  • 17
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 53
  • 1
Kaninchen

Klonalität

  • 45
  • 9
Polyklonal

Konjugat

  • 27
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SMYD3 Antikörper ist unkonjugiert

Applikation

  • 39
  • 12
  • 12
  • 12
  • 8
  • 7
  • 6
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200

    Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat,Cow,Sheep,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human SMYD3

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    SMYD3 (SET and MYND Domain Containing 3 (SMYD3))

    Andere Bezeichnung

    Smyd3

    Hintergrund

    Synonyms: SET and MYND domain containing 3, SET and MYND domain containing protein 3, SMYD 3, SMYD3 protein, Zinc finger MYND domain containing 1, Zinc finger MYND domain containing protein 1, Zinc finger protein subfamily 3A MYND domain containing 1, ZMYND 1, ZMYND1, ZNFN3A1, SMYD3_HUMAN.

    Background: SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.

    Gen-ID

    64754
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