STRADB Antikörper (C-Term)

Produktnummer ABIN8112916

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch STRADB in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für STRADB Antikörper (C-Term) (ABIN8112916)

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRADB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STRADB Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: STRADB Antibody - C-terminal region

Sequenz: GTHTVNSDRL HTPSSKTFSP AFFSLVQLCL QQDPEKRPSA SSLLSHVFFK

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human STRAB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49234-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu STRADB

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Andere Bezeichnung: STRADB

Hintergrund:

Background Information: This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: STE20-related kinase adaptor beta

Alternative Symbols: PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038

Protein Name: STE20-related kinase adapter protein beta

Molekulargewicht: 41kDa

Gen-ID: 55437

UniProt: Q9C0K7

Pathways: AMPK Signaling