SALL3 Antikörper (N-Term)
Kurzübersicht für SALL3 Antikörper (N-Term) (ABIN8111107)
Target
Alle SALL3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- SALL3 Antibody - N-terminal region
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Sequenz
- MSRRKQAKPQ HLKSDEELLP PDGAPEHAAP GEGAEDADSG PESRSGGEET
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Homologie
- Cow: 79%, Dog: 79%, Human: 100%, Mouse: 100%, Pig: 85%, Rat: 100%, Zebrafish: 93%
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SALL3
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39971-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- SALL3 (Sal-Like 3 (SALL3))
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Andere Bezeichnung
- SALL3
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Hintergrund
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Background Information: This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importance in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis.
Gene Name: spalt like transcription factor 3
Alternative Symbols: ZNF796
Protein Name: Sal-like protein 3
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Molekulargewicht
- 143 kDa
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Gen-ID
- 27164
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NCBI Accession
- NP_741996
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UniProt
- Q9BXA9
Target
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