PRDM12 Antikörper (C-Term)

Produktnummer ABIN8108788

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRDM12 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Meerschweinchen und Kaninchen.

Kurzübersicht für PRDM12 Antikörper (C-Term) (ABIN8108788)

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PRDM12 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PRDM12 Antibody - C-terminal region

Sequenz: IPGVPGLEED QKKNKHEDFH PADSAAGPAG RMRCVICHRG FNSRSNLRSH

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PRD12

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33217-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PRDM12

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Andere Bezeichnung: PRDM12

Hintergrund:

Background Information: This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia.

Gene Name: PR/SET domain 12

Alternative Symbols: PFM9, HSAN8

Protein Name: PR domain zinc finger protein 12

Molekulargewicht: 40kDa

Gen-ID: 59335

NCBI Accession: NP_067632

UniProt: Q9H4Q4