CHRNB1 Antikörper (N-Term)
Kurzübersicht für CHRNB1 Antikörper (N-Term) (ABIN8106489)
Target
Alle CHRNB1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- CHRNB1 Antibody - N-terminal region
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Sequenz
- PLAPGVRGSE AEGRLREKLF SGYDSSVRPA REVGDRVRVS VGLILAQLIS
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Homologie
- Cow: 100%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ACHB
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34969-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))
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Andere Bezeichnung
- CHRNB1
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Hintergrund
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Background Information: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
Gene Name: cholinergic receptor nicotinic beta 1 subunit
Alternative Symbols: ACHRB, CHRNB, CMS1D, CMS2A, CMS2C, SCCMS
Protein Name: acetylcholine receptor subunit beta
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Molekulargewicht
- 55kDa
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Gen-ID
- 1140
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NCBI Accession
- NP_000738
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UniProt
- P11230
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Pathways
- Synaptic Membrane
Target
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