MARCH11 Antikörper (C-Term)

Produktnummer ABIN8105161

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MARCH11 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MARCH11 Antikörper (C-Term) (ABIN8105161)

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MARCH11 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: MARCH11 Antibody - C-terminal region

Sequenz: RVFKRWRAVN LHWDVLNYDK ATDIEESSRG ESSTSRTLWL PLTALRNRNL

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MARHB

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43511-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu MARCH11

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Andere Bezeichnung: MARCH11

Hintergrund:

Background Information: MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).[supplied by OMIM, Apr 2010]

Gene Name: membrane associated ring-CH-type finger 11

Alternative Symbols: RNF226, MARCH11, MARCH-XI

Protein Name: E3 ubiquitin-protein ligase MARCH11

Molekulargewicht: 44kDa

Gen-ID: 441061

NCBI Accession: NP_001096032

UniProt: A6NNE9